Research entitled “Synergic Antibiofilm Effect of Thymol and Zinc Oxide Nanoparticles Conjugated with Thiosemicarbazone on Pathogenic Pseudomonas aeruginosa Strains”
was published by the lecturer Asst. Lect. Tabarak Abdul Razzaq Shaghati Al-Kanani in “Arabian Journal for Science and Engineering”
affiliated with
Springer Publishing House
which is classified within the containers (Scopus and Clarivate) and in the first quarter (Q1).
This study considered the antibacterial and biofilm inhibitory activities of ZnO@Glu-TSC nanoparticles on P. aeruginosa due to the emergence of drug resistance, and since the treatment of “Pseudomonas aeruginosa” bacteria poses a major health challenge due to this resistance.
Usually, bacteria in biofilms are more resistant to antibiotics. Therefore, anti-biofilm compounds can be used against bacterial infections.
Zinc oxide (ZnO) nanoparticles were prepared by glutamic acid (ZnO@Glu). Then, the nanoparticles were conjugated with thiosemicarbazone (ZnO@Glu-TSC) and their anti-biofilm activity in combination with thymol was investigated on Pseudomonas aeruginosa strains.
Physicochemical characterization by FT-IR and XRD analyses showed that the nanoparticles were properly synthesized and their purity was demonstrated by EDS mapping.
Thus, treatment with ZnO@Glu-TSC+Thymol could be a new option for eradicating P. aeruginosa biofilms.
Due to the emergence of drug resistance, treating Pseudomonas aeruginosa infections is a major health challenge. In a biofilm, bacteria are usually more resista…

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