{"id":3845,"date":"2024-09-14T13:51:50","date_gmt":"2024-09-14T10:51:50","guid":{"rendered":"https:\/\/pharmacy.alzahraa.edu.iq\/?p=3845"},"modified":"2024-09-14T13:51:50","modified_gmt":"2024-09-14T10:51:50","slug":"synergic-antibiofilm-effect-of-thymol-and-zinc-oxide-nanoparticles-conjugated-with-thiosemicarbazone-on-pathogenic-pseudomonas-aeruginosa-strains","status":"publish","type":"post","link":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/archives\/3845","title":{"rendered":"Synergic Antibiofilm Effect of Thymol and Zinc Oxide Nanoparticles Conjugated with Thiosemicarbazone on Pathogenic Pseudomonas aeruginosa Strains"},"content":{"rendered":"<div class=\"xdj266r x11i5rnm xat24cr x1mh8g0r x1vvkbs x126k92a\">\n<div dir=\"auto\">Research entitled \u201cSynergic Antibiofilm Effect of Thymol and Zinc Oxide Nanoparticles Conjugated with Thiosemicarbazone on Pathogenic Pseudomonas aeruginosa Strains\u201d<\/div>\n<div dir=\"auto\">was published by the lecturer Asst. Lect. Tabarak Abdul Razzaq Shaghati Al-Kanani in \u201cArabian Journal for Science and Engineering\u201d<\/div>\n<div dir=\"auto\">affiliated with<\/div>\n<div dir=\"auto\">Springer Publishing House<\/div>\n<div dir=\"auto\">which is classified within the containers (Scopus and Clarivate) and in the first quarter (Q1).<\/div>\n<\/div>\n<div class=\"x11i5rnm xat24cr x1mh8g0r x1vvkbs xtlvy1s x126k92a\">\n<div dir=\"auto\">This study considered the antibacterial and biofilm inhibitory activities of ZnO@Glu-TSC nanoparticles on P. aeruginosa due to the emergence of drug resistance, and since the treatment of \u201cPseudomonas aeruginosa\u201d bacteria poses a major health challenge due to this resistance.<\/div>\n<div dir=\"auto\">Usually, bacteria in biofilms are more resistant to antibiotics. Therefore, anti-biofilm compounds can be used against bacterial infections.<\/div>\n<div dir=\"auto\">Zinc oxide (ZnO) nanoparticles were prepared by glutamic acid (ZnO@Glu). Then, the nanoparticles were conjugated with thiosemicarbazone (ZnO@Glu-TSC) and their anti-biofilm activity in combination with thymol was investigated on Pseudomonas aeruginosa strains.<\/div>\n<div dir=\"auto\">Physicochemical characterization by FT-IR and XRD analyses showed that the nanoparticles were properly synthesized and their purity was demonstrated by EDS mapping.<\/div>\n<div dir=\"auto\">Thus, treatment with ZnO@Glu-TSC+Thymol could be a new option for eradicating P. aeruginosa biofilms.<\/div>\n<\/div>\n<div class=\"x11i5rnm xat24cr x1mh8g0r x1vvkbs xtlvy1s x126k92a\">\n<div dir=\"auto\">Due to the emergence of drug resistance, treating Pseudomonas aeruginosa infections is a major health challenge. In a biofilm, bacteria are usually more resista\u2026<\/div>\n<\/div>\n<div class=\"x11i5rnm xat24cr x1mh8g0r x1vvkbs xtlvy1s x126k92a\">\n<div dir=\"auto\">Source: SpringerLink <span class=\"html-span xdj266r x11i5rnm xat24cr x1mh8g0r xexx8yu x4uap5 x18d9i69 xkhd6sd x1hl2dhg x16tdsg8 x1vvkbs\"><a class=\"x1i10hfl xjbqb8w x1ejq31n xd10rxx x1sy0etr x17r0tee x972fbf xcfux6l x1qhh985 xm0m39n x9f619 x1ypdohk xt0psk2 xe8uvvx xdj266r x11i5rnm xat24cr x1mh8g0r xexx8yu x4uap5 x18d9i69 xkhd6sd x16tdsg8 x1hl2dhg xggy1nq x1a2a7pz x1sur9pj xkrqix3 x1fey0fg\" tabindex=\"0\" role=\"link\" href=\"https:\/\/l.facebook.com\/l.php?u=https%3A%2F%2Fsearch.app%2FTBywyxSADJxGemzt5%3Ffbclid%3DIwZXh0bgNhZW0CMTAAAR2I-r9izylLlK_STtO8Wa1xWKKVRa5ZB4nqzbGtqL7lQttihItoFcFAyds_aem_PVNINLnZ0DBqvXCjnZpl5w&amp;h=AT3k7myIsL6VvJmOAmgoKjJ0DACUjxElk9Dho4YlZSy8_MQ7or1Zysfq63a72xKlf1mIIqtUoDLQHKwQ8AvL3MYMkLLtCPAh7uw1uAG7HZ786stvGxUy959aCpKxlup29C91&amp;__tn__=-UK-R&amp;c[0]=AT2meK8zNcYLdTfgXHd2IJybemj24UCMHjH5PgZXpVX42jBNVMyzWhM3xwQWWY14LKlJLK_2Smj_pB22BqMTA7xwdfdTJ-mYqcoEdumHdPmaoHJcOj8r6hy2cG0ahlHal_lquyDaNZ3wL-zWlUHyr_L6NScecWbr3itszDtnjPGDpbR8jCSNLmlCZ7TqAmAlnTBjmQ5pH2n35XhWkmqsJ3clPlPhXjvQ2JVu7skacQ\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">https:\/\/search.app\/TBywyxSADJxGemzt5<\/a><\/span><\/div>\n<\/div>\n<div class=\"x11i5rnm xat24cr x1mh8g0r x1vvkbs xtlvy1s x126k92a\">\n<div dir=\"auto\"><span class=\"html-span xdj266r x11i5rnm xat24cr x1mh8g0r xexx8yu x4uap5 x18d9i69 xkhd6sd x1hl2dhg x16tdsg8 x1vvkbs\"><a class=\"x1i10hfl xjbqb8w x1ejq31n xd10rxx x1sy0etr x17r0tee x972fbf xcfux6l x1qhh985 xm0m39n x9f619 x1ypdohk xt0psk2 xe8uvvx xdj266r x11i5rnm xat24cr x1mh8g0r xexx8yu x4uap5 x18d9i69 xkhd6sd x16tdsg8 x1hl2dhg xggy1nq x1a2a7pz x1sur9pj xkrqix3 x1fey0fg\" tabindex=\"0\" role=\"link\" href=\"https:\/\/l.facebook.com\/l.php?u=https%3A%2F%2Fwww.instagram.com%2Fp%2FC_v92LSsiIm%2F%3Figsh%3Dd3lwNjd3bmZ2cjNy%26fbclid%3DIwZXh0bgNhZW0CMTAAAR2I-r9izylLlK_STtO8Wa1xWKKVRa5ZB4nqzbGtqL7lQttihItoFcFAyds_aem_PVNINLnZ0DBqvXCjnZpl5w&amp;h=AT3xli21F6yUrJ3d6oKi7B0fzPgi_OrxDjc3DiNd6_H3iIIL9Jy7u2gj13F88uex1tp_GokKuacfIQniHhp0czJ2ne0FEPN6SU_a85cLZlRCY8dcw1Jun8H7X9EUVT91Loz0&amp;__tn__=-UK-R&amp;c[0]=AT2meK8zNcYLdTfgXHd2IJybemj24UCMHjH5PgZXpVX42jBNVMyzWhM3xwQWWY14LKlJLK_2Smj_pB22BqMTA7xwdfdTJ-mYqcoEdumHdPmaoHJcOj8r6hy2cG0ahlHal_lquyDaNZ3wL-zWlUHyr_L6NScecWbr3itszDtnjPGDpbR8jCSNLmlCZ7TqAmAlnTBjmQ5pH2n35XhWkmqsJ3clPlPhXjvQ2JVu7skacQ\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">https:\/\/www.instagram.com\/p\/C_v92LSsiIm\/&#8230;<\/a><\/span><\/div>\n<\/div>\n<div dir=\"auto\"><\/div>\n<div dir=\"auto\"><\/div>\n<div dir=\"auto\"><img fetchpriority=\"high\" class=\"wp-image-3846 aligncenter\" src=\"https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-176x300.jpg\" alt=\"\" width=\"218\" height=\"372\" srcset=\"https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-176x300.jpg 176w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-600x1023.jpg 600w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-768x1310.jpg 768w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-900x1536.jpg 900w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-7x12.jpg 7w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n-750x1279.jpg 750w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/09\/459405652_122172387668243171_7849366621441755578_n.jpg 938w\" sizes=\"(max-width: 218px) 100vw, 218px\" \/><\/div>","protected":false},"excerpt":{"rendered":"<p>\u062a\u0645 \u0646\u0634\u0631 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0645\u0648\u0633\u0648\u0645 ( Synergic Antibiofilm Effect of Thymol and Zinc Oxide Nanoparticles Conjugated with Thiosemicarbazone &#8230; 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