{"id":3689,"date":"2024-05-28T12:25:44","date_gmt":"2024-05-28T09:25:44","guid":{"rendered":"https:\/\/pharmacy.alzahraa.edu.iq\/?p=3689"},"modified":"2024-05-28T12:25:44","modified_gmt":"2024-05-28T09:25:44","slug":"evaluation-the-cytotoxic-effect-of-fe3o4glu-gingerol-on-lung-adenocarcinoma-cell-line-a549-with-biological-mechanisms","status":"publish","type":"post","link":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/archives\/3689","title":{"rendered":"(Evaluation the cytotoxic effect of Fe3O4@Glu-Gingerol on lung adenocarcinoma cell line (A549) with biological mechanisms)"},"content":{"rendered":"<p>Lecturer Asst. Lect. Tabarak Abdulrazzaq Shaghati Al-Kanan published a research entitled \u201cEvaluation of the cytotoxic effect of Fe3O4@Glu-Gingerol on lung adenocarcinoma cell line (A549) with biological mechanism\u201d in (Heliyon) Journal which is classified in the (first) quarter of the Scopus and Clarivate container.<br class=\"html-br\" \/>adenocarcinoma cell line (A549) with biological mechanisms)<br class=\"html-br\" \/><br class=\"html-br\" \/>The research included \u201cThe use of nanotechnology products with super magnetic properties to deliver drugs in a targeted manner with great interest recently<br class=\"html-br\" \/>due to the anticancer properties of gingerol, the main phenolic compound of ginger.<br class=\"html-br\" \/><br class=\"html-br\" \/>This study aimed to prepare Fe3O4@Glucose-Gingerol nanoparticles NPs and investigate their anti-cancer potential in lung adenocarcinoma cell line.<br class=\"html-br\" \/>. The physical and chemical properties of the nanoparticles were studied using FT-IR, XRD<br class=\"html-br\" \/>zeta potential, DLS, EDS, mapping, VSM, and electron microscopy imaging. Cell lines were examined A549 \u201clung adenocarcinoma\u201d and MRC-5 (normal) cell lines by MTT assay.<br class=\"html-br\" \/>This study revealed that Fe3O4@Glu-Gingerol NPs<br class=\"html-br\" \/>have anti proliferative effects on lung adenocarcinoma cell line<br class=\"html-br\" \/>line by activating intrinsic<br class=\"html-br\" \/>and extrinsic apoptosis which is a promising feature<br class=\"html-br\" \/>in cancer therapy.<\/p>\n<p><img fetchpriority=\"high\" class=\"wp-image-3690 aligncenter\" src=\"https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-210x300.jpg\" alt=\"\" width=\"284\" height=\"406\" srcset=\"https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-210x300.jpg 210w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-718x1024.jpg 718w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-768x1095.jpg 768w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-1077x1536.jpg 1077w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-8x12.jpg 8w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-600x856.jpg 600w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n-750x1070.jpg 750w, https:\/\/pharmacy.alzahraa.edu.iq\/wp-content\/uploads\/2024\/05\/442483221_122139217442243171_5542513886809841710_n.jpg 1122w\" sizes=\"(max-width: 284px) 100vw, 284px\" \/><\/p>","protected":false},"excerpt":{"rendered":"<p>\u062a\u0645 \u0646\u0634\u0631 \u0627\u0644\u0628\u062d\u062b \u0627\u0644\u0645\u0648\u0633\u0648\u0645 (Evaluation the cytotoxic effect of Fe3O4@Glu-Gingerol on lungadenocarcinoma cell line (A549) with biological &#8230; <a class=\"cz_readmore\" href=\"https:\/\/pharmacy.alzahraa.edu.iq\/en\/archives\/3689\"><i class=\"fas fa-chevron-left\" aria-hidden=\"true\"><\/i><span>Read more<\/span><\/a><\/p>","protected":false},"author":2,"featured_media":3690,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[17],"tags":[],"_links":{"self":[{"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/posts\/3689"}],"collection":[{"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/comments?post=3689"}],"version-history":[{"count":1,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/posts\/3689\/revisions"}],"predecessor-version":[{"id":3691,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/posts\/3689\/revisions\/3691"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/media\/3690"}],"wp:attachment":[{"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/media?parent=3689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/categories?post=3689"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmacy.alzahraa.edu.iq\/en\/wp-json\/wp\/v2\/tags?post=3689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}